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BIITE: A Tool to Determine HLA Class II Epitopes from T Cell ELISpot Data

Activation of CD4(+) T cells requires the recognition of peptides that are presented by HLA class II molecules and can be assessed experimentally using the ELISpot assay. However, even given an individual’s HLA class II genotype, identifying which class II molecule is responsible for a positive ELIS...

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Bibliographic Details
Published in:PLoS Comput Biol
Main Authors: Boelen, Lies, O’Neill, Patrick K., Quigley, Kathryn J., Reynolds, Catherine J., Maillere, Bernard, Robinson, John H., Lertmemongkolchai, Ganjana, Altmann, Daniel M., Boyton, Rosemary J., Asquith, Becca
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783075/
https://ncbi.nlm.nih.gov/pubmed/26953935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004796
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