The serodominant secreted effector protein of Salmonella, SseB, is a strong CD4 antigen containing an immunodominant epitope presented by diverse HLA class II alleles

Detailed characterization of the protective T-cell response in salmonellosis is a pressing unmet need in light of the global burden of human Salmonella infections and the likely contribution of CD4 T cells to immunity against this intracellular infection. In previous studies screening patient sera a...

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Main Authors: Reynolds, Catherine J, Jones, Claire, Blohmke, Christoph J, Darton, Thomas C, Goudet, Amelie, Sergeant, Ruhena, Maillere, Bernard, Pollard, Andrew J, Altmann, Daniel M, Boyton, Rosemary J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212957/
https://ncbi.nlm.nih.gov/pubmed/24891088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12327
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