T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses

Zika virus (ZIKV) Infection has several outcomes from asymptomatic exposure to rash, conjunctivitis, Guillain-Barré syndrome or congenital Zika syndrome. Analysis of ZIKV immunity is confounded by the fact that several related Flaviviruses infect humans, including Dengue virus 1–4, West Nile virus a...

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Udgivet i:Sci Rep
Main Authors: Reynolds, C. J., Suleyman, O. M., Ortega-Prieto, A. M., Skelton, J. K., Bonnesoeur, P., Blohm, A., Carregaro, V., Silva, J. S., James, E. A., Maillère, B., Dorner, M., Boyton, R. J., Altmann, D. M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766511/
https://ncbi.nlm.nih.gov/pubmed/29330423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18781-1
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