Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C

Natural killer (NK) cells have an important role in immune defense against viruses and cancer. Activation of human NK cell cytotoxicity toward infected or tumor cells is regulated by killer cell immunoglobulin-like receptors (KIRs) that bind to human leukocyte antigen class I (HLA-I). Combinations o...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sim, Malcolm J. W., Rajagopalan, Sumati, Altmann, Daniel M., Boyton, Rosemary J., Sun, Peter D., Long, Eric O.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601252/
https://ncbi.nlm.nih.gov/pubmed/31138701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903781116
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