Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C

Natural killer (NK) cells have an important role in immune defense against viruses and cancer. Activation of human NK cell cytotoxicity toward infected or tumor cells is regulated by killer cell immunoglobulin-like receptors (KIRs) that bind to human leukocyte antigen class I (HLA-I). Combinations o...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Sim, Malcolm J. W., Rajagopalan, Sumati, Altmann, Daniel M., Boyton, Rosemary J., Sun, Peter D., Long, Eric O.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601252/
https://ncbi.nlm.nih.gov/pubmed/31138701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903781116
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