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CD4(+) T cell epitopes of FliC conserved between strains of Burkholderia - implications for vaccines against melioidosis and Cepacia Complex in Cystic Fibrosis

Burkholderia pseudomallei (Bp), is the causative agent of melioidosis, characterized by pneumonia and fatal septicemia and prevalent in SE Asia. Related Burkholderia species are strong risk factors of mortality in cystic fibrosis (CF). The Bp flagellar protein FliC is strongly seroreactive and vacci...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Musson, Julie A., Reynolds, Catherine J, Rinchai, Darawan, Nithichanon, Arnone, Khaenam, Prasong, Favry, Emmanuel, Spink, Natasha, Chu, Karen KY, De Soyza, Anthony, Bancroft, Gregory J, Lertmemongkolchai, Ganjana, Maillere, Bernard, Boyton, Rosemary J, Altmann, Daniel M., Robinson, John H.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258416/
https://ncbi.nlm.nih.gov/pubmed/25392525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402273
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