Cargando...

Frataxin Deficiency Promotes Excess Microglial DNA Damage and Inflammation that Is Rescued by PJ34

An inherited deficiency in the frataxin protein causes neurodegeneration of the dorsal root ganglia and Friedreich's ataxia (FA). Frataxin deficiency leads to oxidative stress and inflammatory changes in cell and animal models; however, the cause of the inflammatory changes, and especially what...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Shen, Yan, McMackin, Marissa Z., Shan, Yuxi, Raetz, Alan, David, Sheila, Cortopassi, Gino
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783034/
https://ncbi.nlm.nih.gov/pubmed/26954031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151026
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!