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Frataxin Deficiency Induces Schwann Cell Inflammation and Death

Mutations in the frataxin gene cause dorsal root ganglion demyelination and neurodegeneration, which leads to Friedreich’s ataxia. However the consequences of frataxin depletion have not been measured in dorsal root ganglia or Schwann cells. We knocked down frataxin in several neural cell lines, inc...

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Detalhes bibliográficos
Main Authors: Lu, Chunye, Schoenfeld, Robert, Shan, Yuxi, Tsai, Cindy, Hammock, Bruce, Cortopassi, Gino
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563672/
https://ncbi.nlm.nih.gov/pubmed/19679182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2009.07.011
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