Clotting activity of polyphosphate functionalized silica nanoparticles()

We present a silica nanoparticle (SNP) functionalized with polyphosphate (polyP) that accelerate the body’s natural clotting process. SNPs initiate the blood clotting system’s contact pathway; short-chain polyP accelerates the common pathway via rapid formation of thrombin. This enhances the overall...

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Udgivet i:Angew Chem Int Ed Engl
Main Authors: Kudela, Damien, Smith, Stephanie A., May-Masnou, Anna, Braun, Gary B., Pallaoro, Alessia, Nguyen, Chi K., Chuong, Tracy T., Nownes, Sara, Allen, Riley, Parker, Nicholas R., Rashidi, Hooman H., Morrissey, James H., Stucky, Galen D.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782980/
https://ncbi.nlm.nih.gov/pubmed/25651530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201409639
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