Inhibition of hypoxia-inducible factor via upregulation of von Hippel-Lindau protein induces “angiogenic switch off” in a hepatoma mouse model

“Angiogenic switch off” is one of the ideal therapeutic concepts in the treatment of cancer. However, the specific molecules which can induce “angiogenic switch off” in tumor have not been identified yet. In this study, we focused on von Hippel-Lindau protein (pVHL) in hepatocellular carcinoma (HCC)...

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Bibliografiset tiedot
Julkaisussa:Mol Ther Oncolytics
Päätekijät: Iwamoto, Hideki, Nakamura, Toru, Koga, Hironori, Izaguirre-Carbonell, Jesus, Kamisuki, Shinji, Sugawara, Fumio, Abe, Mitsuhiko, Iwabata, Kazuki, Ikezono, Yu, Sakaue, Takahiko, Masuda, Atsutaka, Yano, Hirohisa, Ohta, Keisuke, Nakano, Masahito, Shimose, Shigeo, Shirono, Tomotake, Torimura, Takuji
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782957/
https://ncbi.nlm.nih.gov/pubmed/27119112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2015.20
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