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Retargeted oncolytic adenovirus displaying a single variable domain of camelid heavy-chain-only antibody in a fiber protein

Conditionally replicative adenoviruses are promising agents for oncolytic virotherapy. Various approaches have been attempted to retarget adenoviruses to tumor-specific antigens to circumvent deficiency of receptor for adenoviral binding and to provide an additional level of tumor specificity. Funct...

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Foilsithe in:Mol Ther Oncolytics
Main Authors: van Erp, Elisabeth A, Kaliberova, Lyudmila N, Kaliberov, Sergey A, Curiel, David T
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782946/
https://ncbi.nlm.nih.gov/pubmed/27119101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2015.1
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