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Experimental virotherapy of chemoresistant pancreatic carcinoma using infectivity-enhanced fiber-mosaic oncolytic adenovirus

Pancreatic cancer is a significant clinical problem and novel therapeutic approaches are desperately needed. Recent advances in conditionally replicative adenovirus-based (CRAd) oncolytic virus design allow the application of CRAd vectors as a therapeutic strategy to efficiently target and eradicate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kaliberov, Sergey A., Kaliberova, Lyudmila N., Buchsbaum, Donald J., Curiel, David T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157623/
https://ncbi.nlm.nih.gov/pubmed/24903014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2014.26
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