Adenoviral targeting using genetically incorporated camelid single variable domains

The unique ability of human adenovirus serotype 5 (Ad5) to accomplish efficient transduction has allowed the use of Ad5-based vectors for a range of gene therapy applications. Several strategies have been developed to alter tropism of Ad vectors to achieve a cell-specific gene delivery by employing...

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Hlavní autoři: Kaliberov, Sergey A., Kaliberova, Lyudmila N., Buggio, Maurizio, Tremblay, Jacqueline M., Shoemaker, Charles B., Curiel, David T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157633/
https://ncbi.nlm.nih.gov/pubmed/24933423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2014.82
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