Transcriptional Targeting of Primary and Metastatic Tumor Neovasculature by an Adenoviral Type 5 Roundabout4 Vector in Mice

New approaches targeting metastatic neovasculature are needed. Payload capacity, cellular transduction efficiency, and first-pass cellular uptake following systemic vector administration, motivates persistent interest in tumor vascular endothelial cell (EC) adenoviral (Ad) vector targeting. While EC...

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Bibliographic Details
Main Authors: Lu, Zhi Hong, Kaliberov, Sergey, Sohn, Rebecca E., Kaliberova, Lyudmila, Curiel, David T., Arbeit, Jeffrey M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871592/
https://ncbi.nlm.nih.gov/pubmed/24376772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083933
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