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The myeloid binding peptide adenoviral vector enables multi-organ vascular endothelial gene targeting

Vascular endothelial cells (ECs) are ideal gene therapy targets as they provide widespread tissue access and are the first contact surfaces following intravenous vector administration. Human recombinant adenovirus serotype 5 (Ad5) is the most frequently used gene transfer system because of its appre...

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Detalhes bibliográficos
Main Authors: Lu, Zhi Hong, Kaliberov, Sergey, Zhang, Jingzhu, Muz, Barbara, Azab, Abdel Kareem, Sohn, Rebecca E., Kaliberova, Lyudmila, Du, Yingqiu, Curiel, David T., Arbeit, Jeffrey M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117817/
https://ncbi.nlm.nih.gov/pubmed/24955893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2014.78
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