Retargeting of Gene Expression Using Endothelium Specific Hexon Modified Adenoviral Vector

Adenovirus serotype 5 (Ad5) vectors are well suited for gene therapy. However, tissue-selective transduction by systemically administered Ad5-based vectors is confounded by viral particle sequestration in the liver. Hexon-modified Ad5 expressing reporter gene under transcriptional control by the imm...

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Bibliographic Details
Main Authors: Kaliberov, Sergey A., Kaliberova, Lyudmila N., Lu, Zhi Hong, Preuss, Meredith A., Barnes, Justin A., Stockard, Cecil R., Grizzle, William E., Arbeit, Jeffrey M., Curiel, David T.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894856/
https://ncbi.nlm.nih.gov/pubmed/24210128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.09.020
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