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Retargeting of Gene Expression Using Endothelium Specific Hexon Modified Adenoviral Vector
Adenovirus serotype 5 (Ad5) vectors are well suited for gene therapy. However, tissue-selective transduction by systemically administered Ad5-based vectors is confounded by viral particle sequestration in the liver. Hexon-modified Ad5 expressing reporter gene under transcriptional control by the imm...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3894856/ https://ncbi.nlm.nih.gov/pubmed/24210128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.09.020 |
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