Combinatorial treatment with oncolytic adenovirus and helper-dependent adenovirus augments adenoviral cancer gene therapy

Oncolytic adenoviruses (Onc.Ads) produce significant antitumor effects but as single agents they rarely eliminate tumors. Investigators have therefore incorporated sequences into these vectors that encode immunomodulatory molecules to enhance antitumor immunity. Successful implementation of this str...

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Detaylı Bibliyografya
Yayımlandı:Mol Ther Oncolytics
Asıl Yazarlar: Farzad, Lisa, Cerullo, Vincenzo, Yagyu, Shigeki, Bertin, Terry, Hemminki, Akseli, Rooney, Cliona, Lee, Brendan, Suzuki, Masataka
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782941/
https://ncbi.nlm.nih.gov/pubmed/27119096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2014.8
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