Cargando...
Visualization of APP and BACE-1 approximation in neurons: new insights into the amyloidogenic pathway
Cleavage of APP (amyloid precursor protein) by BACE-1 (β-site APP cleaving enzyme-1) is the rate-limiting step in amyloid-beta (Aβ) production and a neuropathologic hallmark of Alzheimer's disease (AD); thus physical approximation of this substrate-enzyme pair is a critical event with broad bio...
Gardado en:
| Publicado en: | Nat Neurosci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4782935/ https://ncbi.nlm.nih.gov/pubmed/26642089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4188 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|