Tissue-independent and tissue-specific patterns of DNA methylation alteration in cancer

BACKGROUND: There is growing evidence that DNA methylation alterations contribute to carcinogenesis. While cancer tissue exhibits widespread DNA methylation changes, the proportion of tissue-specific versus tissue-independent DNA methylation alterations in cancer is unclear. In addition, it is unkno...

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Bibliografiske detaljer
Udgivet i:Epigenetics Chromatin
Main Authors: Chen, Yuting, Breeze, Charles E., Zhen, Shao, Beck, Stephan, Teschendorff, Andrew E.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782576/
https://ncbi.nlm.nih.gov/pubmed/26958079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0058-4
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