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EPISCORE: cell type deconvolution of bulk tissue DNA methylomes from single-cell RNA-Seq data
Cell type heterogeneity presents a challenge to the interpretation of epigenome data, compounded by the difficulty in generating reliable single-cell DNA methylomes for large numbers of cells and samples. We present EPISCORE, a computational algorithm that performs virtual microdissection of bulk ti...
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| Publié dans: | Genome Biol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7650528/ https://ncbi.nlm.nih.gov/pubmed/32883324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02126-9 |
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