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Identification of differentially methylated cell-types in Epigenome-Wide Association Studies

An outstanding challenge of Epigenome-Wide Association Studies (EWAS) performed in complex tissues is the identification of the specific cell-type(s) responsible for the observed differential DNA methylation. Here, we present a novel statistical algorithm, called CellDMC, which is able to identify n...

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Bibliografiset tiedot
Julkaisussa:Nat Methods
Päätekijät: Zheng, Shijie C, Breeze, Charles E., Beck, Stephan, Teschendorff, Andrew E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277016/
https://ncbi.nlm.nih.gov/pubmed/30504870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0213-x
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