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A comparison of reference-based algorithms for correcting cell-type heterogeneity in Epigenome-Wide Association Studies
BACKGROUND: Intra-sample cellular heterogeneity presents numerous challenges to the identification of biomarkers in large Epigenome-Wide Association Studies (EWAS). While a number of reference-based deconvolution algorithms have emerged, their potential remains underexplored and a comparative evalua...
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| Veröffentlicht in: | BMC Bioinformatics |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5307731/ https://ncbi.nlm.nih.gov/pubmed/28193155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1511-5 |
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