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Cell and tissue type independent age-associated DNA methylation changes are not rare but common

Age-associated DNA methylation changes have been widely reported across many different tissue and cell types. Epigenetic ‘clocks’ that can predict chronological age with a surprisingly high degree of accuracy appear to do so independently of tissue and cell-type, suggesting that a component of epige...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Zhu, Tianyu, Zheng, Shijie C, Paul, Dirk S., Horvath, Steve, Teschendorff, Andrew E.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286821/
https://ncbi.nlm.nih.gov/pubmed/30482885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101666
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