Cas3 is a limiting factor for CRISPR-Cas immunity in Escherichia coli cells lacking H-NS

BACKGROUND: CRISPR-Cas systems provide adaptive immunity to mobile genetic elements in prokaryotes. In many bacteria, including E. coli, a specialized ribonucleoprotein complex called Cascade enacts immunity by“ an interference reaction" between CRISPR encoded RNA (crRNA) and invader DNA sequen...

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Bibliographic Details
Published in:BMC Microbiol
Main Authors: Majsec, Kristina, Bolt, Edward L., Ivančić-Baće, Ivana
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782391/
https://ncbi.nlm.nih.gov/pubmed/26956996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-016-0643-5
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