Loading...
CRISPR–Cas adaptation in Escherichia coli requires RecBCD helicase but not nuclease activity, is independent of homologous recombination, and is antagonized by 5′ ssDNA exonucleases
Prokaryotic adaptive immunity is established against mobile genetic elements (MGEs) by ‘naïve adaptation’ when DNA fragments from a newly encountered MGE are integrated into CRISPR–Cas systems. In Escherichia coli, DNA integration catalyzed by Cas1–Cas2 integrase is well understood in mechanistic an...
Na minha lista:
| Udgivet i: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2018
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6212769/ https://ncbi.nlm.nih.gov/pubmed/30189098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky799 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|