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CRISPR-Cas immunity, DNA repair and genome stability

Co-opting of CRISPR-Cas ‘Interference’ reactions for editing the genomes of eukaryotic and prokaryotic cells has highlighted crucial support roles for DNA repair systems that strive to maintain genome stability. As front-runners in genome editing that targets DNA, the class 2 CRISPR-Cas enzymes Cas9...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Cubbon, Andrew, Ivancic-Bace, Ivana, Bolt, Edward L.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6147917/
https://ncbi.nlm.nih.gov/pubmed/30209206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20180457
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