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Topological domain structure of the Escherichia coli chromosome

The circular chromosome of Escherichia coli is organized into independently supercoiled loops, or topological domains. We investigated the organization and size of these domains in vivo and in vitro. Using the expression of >300 supercoiling-sensitive genes to gauge local chromosomal supercoiling...

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Autors principals: Postow, Lisa, Hardy, Christine D., Arsuaga, Javier, Cozzarelli, Nicholas R.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC478196/
https://ncbi.nlm.nih.gov/pubmed/15256503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1207504
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