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Topological domain structure of the Escherichia coli chromosome

The circular chromosome of Escherichia coli is organized into independently supercoiled loops, or topological domains. We investigated the organization and size of these domains in vivo and in vitro. Using the expression of >300 supercoiling-sensitive genes to gauge local chromosomal supercoiling, w...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Principais autores: Postow, Lisa, Hardy, Christine D., Arsuaga, Javier, Cozzarelli, Nicholas R.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2004
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC478196/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15256503/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1207504
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