Topoisomerase IV, not gyrase, decatenates products of site-specific recombination in Escherichia coli

DNA replication and recombination generate intertwined DNA intermediates that must be decatenated for chromosome segregation to occur. We showed recently that topoisomerase IV (topo IV) is the only important decatenase of DNA replication intermediates in bacteria. Earlier results, however, indicated...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Zechiedrich, E. Lynn, Khodursky, Arkady B., Cozzarelli, Nicholas R.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1997
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316566/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9334322/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.11.19.2580
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