Dynamics of DNA supercoiling by transcription in Escherichia coli.

The relative rotation between RNA polymerase and DNA during transcription elongation can lead to supercoiling of the DNA template. However, the variables that influence the efficiency of supercoiling by RNA polymerase in vivo are poorly understood, despite the importance of supercoiling for DNA meta...

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Bibliographic Details
Main Authors: Cook, D N, Ma, D, Pon, N G, Hearst, J E
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC50389/
https://ncbi.nlm.nih.gov/pubmed/1332053
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