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Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

In mammalian cells, both microRNAs (miRNAs) and small interfering RNAs (siRNAs) are thought to be loaded into the same RNA-induced silencing complex (RISC), where they guide mRNA degradation or translation silencing depending on the complementarity of the target. In Drosophila, Argonaute2 (AGO2) was...

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Bibliografiska uppgifter
Huvudupphovsmän: Okamura, Katsutomo, Ishizuka, Akira, Siomi, Haruhiko, Siomi, Mikiko C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2004
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC478188/
https://ncbi.nlm.nih.gov/pubmed/15231716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1210204
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