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Distinct mechanisms for microRNA strand selection by Drosophila Argonautes
In Drosophila, miRNA strands are predominantly sorted into AGO1 to regulate seed-matched target transcripts, while their partner miRNA* strands are thought to be mostly degraded. Here we report that Drosophila Argonautes exhibit different strand preferences for miRNA duplexes, and that in particular...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785079/ https://ncbi.nlm.nih.gov/pubmed/19917251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.09.027 |
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