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Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster
Cis-natural antisense transcripts (cis-NATs) have been speculated to be substrates for endogenous RNA interference (RNAi), but little experimental evidence for such a pathway in animals has been reported. Analysis of massive Drosophila melanogaster small RNA data sets now reveals two mechanisms that...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713754/ https://ncbi.nlm.nih.gov/pubmed/18500351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1438 |
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