Drosophila melanogaster retrotransposon and inverted repeat-derived endogenous siRNAs are differentially processed in distinct cellular locations

BACKGROUND: Endogenous small interfering (esi)RNAs repress mRNA levels and retrotransposon mobility in Drosophila somatic cells by poorly understood mechanisms. 21 nucleotide esiRNAs are primarily generated from retrotransposons and two inverted repeat (hairpin) loci in Drosophila culture cells in a...

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Pubblicato in:BMC Genomics
Autori principali: Harrington, Andrew W., McKain, Michael R., Michalski, Daniel, Bauer, Kaylyn M., Daugherty, Joshua M., Steiniger, Mindy
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392987/
https://ncbi.nlm.nih.gov/pubmed/28415970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3692-8
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