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Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways
In mammalian cells, both microRNAs (miRNAs) and small interfering RNAs (siRNAs) are thought to be loaded into the same RNA-induced silencing complex (RISC), where they guide mRNA degradation or translation silencing depending on the complementarity of the target. In Drosophila, Argonaute2 (AGO2) was...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC478188/ https://ncbi.nlm.nih.gov/pubmed/15231716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1210204 |
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