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A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

The IRF3 transcription factor is critical for the first line of defense against pathogens mainly through interferon β and antiviral gene expression. A detailed analysis of IRF3 activation is essential to understand how pathogens induce or evade the innate antiviral response. Distinct activated forms...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Vis Exp
Prif Awduron: Robitaille, Alexa C., Mariani, Mélissa K., Fortin, Audray, Grandvaux, Nathalie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MyJove Corporation 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781702/
https://ncbi.nlm.nih.gov/pubmed/26862747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53723
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