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A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
The IRF3 transcription factor is critical for the first line of defense against pathogens mainly through interferon β and antiviral gene expression. A detailed analysis of IRF3 activation is essential to understand how pathogens induce or evade the innate antiviral response. Distinct activated forms...
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| Udgivet i: | J Vis Exp |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MyJove Corporation
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4781702/ https://ncbi.nlm.nih.gov/pubmed/26862747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53723 |
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