The Combination of IFN β and TNF Induces an Antiviral and Immunoregulatory Program via Non-Canonical Pathways Involving STAT2 and IRF9

Interferon (IFN) β and Tumor Necrosis Factor (TNF) are key players in immunity against viruses. Compelling evidence has shown that the antiviral and inflammatory transcriptional response induced by IFNβ is reprogrammed by crosstalk with TNF. IFNβ mainly induces interferon-stimulated genes by the Jan...

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Publicado no:Cells
Main Authors: Mariani, Mélissa K., Dasmeh, Pouria, Fortin, Audray, Caron, Elise, Kalamujic, Mario, Harrison, Alexander N., Hotea, Diana I., Kasumba, Dacquin M., Cervantes-Ortiz, Sandra L., Mukawera, Espérance, Serohijos, Adrian W. R., Grandvaux, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721756/
https://ncbi.nlm.nih.gov/pubmed/31426476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8080919
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