IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH Oxidase-mediated airway antiviral response

Airway epithelial cells are key initial innate immune responders in the fight against respiratory viruses, primarily via the secretion of antiviral and proinflammatory cytokines that act in an autocrine/paracrine fashion to trigger the establishment of an antiviral state. It is currently thought tha...

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Sonraí Bibleagrafaíochta
Main Authors: Fink, Karin, Martin, Lydie, Mukawera, Esperance, Chartier, Stéfany, De Deken, Xavier, Brochiero, Emmanuelle, Miot, Françoise, Grandvaux, Nathalie
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2013
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641604/
https://ncbi.nlm.nih.gov/pubmed/23545780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.47
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