Redox-modulating agents target NOX2-dependent IKKε oncogenic kinase expression and proliferation in human breast cancer cell lines

Oxidative stress is considered a causative factor in carcinogenesis, but also in the development of resistance to current chemotherapies. The appropriate usage of redox-modulating compounds is limited by the lack of knowledge of their impact on specific molecular pathways. Increased levels of the IK...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Mukawera, Espérance, Chartier, Stefany, Williams, Virginie, Pagano, Patrick J., Lapointe, Réjean, Grandvaux, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511630/
https://ncbi.nlm.nih.gov/pubmed/26177467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.06.010
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