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Detection of IKKε by immunohistochemistry in primary breast cancer: association with EGFR expression and absence of lymph node metastasis

BACKGROUND: IKKε is an oncogenic kinase that was found amplified and overexpressed in a substantial percentage of human breast cancer cell lines and primary tumors using genomic and gene expression analyses. Molecular studies have provided the rational for a key implication of IKKε in breast cancer...

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Publicado en:BMC Cancer
Main Authors: Williams, Virginie, Grosset, Andrée-Anne, Zamorano Cuervo, Natalia, St-Pierre, Yves, Sylvestre, Marie-Pierre, Gaboury, Louis, Grandvaux, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441089/
https://ncbi.nlm.nih.gov/pubmed/28532474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3321-6
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