Assessment of thiopurine methyltransferase activity in patients prescribed azathioprine or other thiopurine-based drugs.

OBJECTIVES: To examine whether pretreatment determination of thiopurine methyltransferase (TPMT) enzymatic activity (phenotyping) or TPMT genotype, to guide thiopurine therapy in chronic autoimmune disease patients, reduces treatment harms. Other objectives included assessing: preanalytic, analytic,...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Evid Rep Technol Assess (Full Rep)
Main Authors: Booth, Ronald A, Ansari, Mohammed T, Tricco, Andrea C, Loit, Evelin, Weeks, Laura, Doucette, Steve, Skidmore, Becky, Hoch, Jeffrey S, Tsouros, Sophia, Sears, Margaret, Sy, Richmond, Karsh, Jacob, Mani, Suja, Galipeau, James, Yurkiewich, Alexander, Daniel, Raymond, Tsertsvadze, Alexander, Yazdi, Fatemeh
פורמט: Artigo
שפה:Inglês
יצא לאור: United States. Agency for Healthcare Research and Quality 2010
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781432/
https://ncbi.nlm.nih.gov/pubmed/23126559
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