Decreased signaling competence as a result of receptor overexpression: overexpression of CD4 reduces its ability to activate p56lck tyrosine kinase and to regulate T-cell antigen receptor expression in immature CD4+CD8+ thymocytes.

مواد مشابهة

• ZAP-70 Protein Promotes Tyrosine Phosphorylation of T Cell Receptor Signaling Motifs (ITAMs) in Immature CD4(+)8(+) Thymocytes with Limiting p56(lck)
  بواسطة: Ashe, Jennifer M., وآخرون
  منشور في: (1999)
• Ligand-stimulated signaling events in immature CD4+CD8+ thymocytes expressing competent T-cell receptor complexes.
  بواسطة: Nakayama, T, وآخرون
  منشور في: (1991)
• Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules
  منشور في: (1993)
• Inhibition of T-cell receptor beta-chain gene rearrangement by overexpression of the non-receptor protein tyrosine kinase p56lck.
  بواسطة: Anderson, S J, وآخرون
  منشور في: (1992)
• Subcellular localization of T-cell receptor complexes containing tyrosine-phosphorylated zeta proteins in immature CD4+CD8+ thymocytes.
  بواسطة: Kearse, K P, وآخرون
  منشور في: (1993)