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ZAP-70 Protein Promotes Tyrosine Phosphorylation of T Cell Receptor Signaling Motifs (ITAMs) in Immature CD4(+)8(+) Thymocytes with Limiting p56(lck)

As a result of interaction with epithelial cells in the thymic cortex, immature CD4(+)8(+) (double positive, DP) thymocytes express relatively few T cell receptors (TCRs) and contain diminished numbers of coreceptor-associated p56(lck) (lck) PTK molecules. As a result, TCR signal transduction in DP...

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書目詳細資料
Main Authors: Ashe, Jennifer M., Wiest, David L., Abe, Ryo, Singer, Alfred
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193013/
https://ncbi.nlm.nih.gov/pubmed/10190908
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