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ZAP-70 Protein Promotes Tyrosine Phosphorylation of T Cell Receptor Signaling Motifs (ITAMs) in Immature CD4(+)8(+) Thymocytes with Limiting p56(lck)
As a result of interaction with epithelial cells in the thymic cortex, immature CD4(+)8(+) (double positive, DP) thymocytes express relatively few T cell receptors (TCRs) and contain diminished numbers of coreceptor-associated p56(lck) (lck) PTK molecules. As a result, TCR signal transduction in DP...
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Main Authors: | , , , |
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格式: | Artigo |
語言: | Inglês |
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The Rockefeller University Press
1999
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在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193013/ https://ncbi.nlm.nih.gov/pubmed/10190908 |
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