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Insulin/insulin-like growth factor signaling in C. elegans.
The C. elegans insulin/IGF-1 signaling (IIS) pathway connects nutrient levels to metabolism, growth, development, longevity, and behavior. This fundamental pathway is regulated by insulin-like peptide ligands that bind to the insulin/IGF-1 transmembrane receptor (IGFR) ortholog DAF-2. DAF-2/IGFR con...
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| Udgivet i: | WormBook |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
s.n.]
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4780952/ https://ncbi.nlm.nih.gov/pubmed/24395814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1895/wormbook.1.164.1 |
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