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Insulin/insulin-like growth factor signaling in C. elegans.

The C. elegans insulin/IGF-1 signaling (IIS) pathway connects nutrient levels to metabolism, growth, development, longevity, and behavior. This fundamental pathway is regulated by insulin-like peptide ligands that bind to the insulin/IGF-1 transmembrane receptor (IGFR) ortholog DAF-2. DAF-2/IGFR con...

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Bibliografiske detaljer
Udgivet i:WormBook
Main Authors: Murphy, Coleen T, Hu, Patrick J
Format: Artigo
Sprog:Inglês
Udgivet: s.n.] 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780952/
https://ncbi.nlm.nih.gov/pubmed/24395814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1895/wormbook.1.164.1
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