Reduced Insulin/Insulin-like Growth Factor-1 Signaling and Dietary Restriction Inhibit Translation but Preserve Muscle Mass in Caenorhabditis elegans

Reduced signaling through the C. elegans insulin/insulin-like growth factor-1-like tyrosine kinase receptor daf-2 and dietary restriction via bacterial dilution are two well-characterized lifespan-extending interventions that operate in parallel or through (partially) independent mechanisms. Using a...

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Detalhes bibliográficos
Main Authors: Depuydt, Geert, Xie, Fang, Petyuk, Vladislav A., Shanmugam, Nilesh, Smolders, Arne, Dhondt, Ineke, Brewer, Heather M., Camp, David G., Smith, Richard D., Braeckman, Bart P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861712/
https://ncbi.nlm.nih.gov/pubmed/24002365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.027383
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