Changes of Protein Turnover in Aging Caenorhabditis elegans

Protein turnover rates severely decline in aging organisms, including C. elegans. However, limited information is available on turnover dynamics at the individual protein level during aging. We followed changes in protein turnover at one-day resolution using a multiple-pulse (15)N-labeling and accur...

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Udgivet i:Mol Cell Proteomics
Main Authors: Dhondt, Ineke, Petyuk, Vladislav A., Bauer, Sophie, Brewer, Heather M., Smith, Richard D., Depuydt, Geert, Braeckman, Bart P.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587862/
https://ncbi.nlm.nih.gov/pubmed/28679685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000049
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