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Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases

The rapid emergence of multi-drug resistant bacteria has accelerated the need for novel therapeutic approaches to counter life-threatening infections. The persistence of bacterial infection is often associated with quorum-sensing-mediated biofilm formation. Thus, the disruption of this signaling cir...

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Dettagli Bibliografici
Pubblicato in:J Vis Exp
Autori principali: Tay, Song Buck, Chow, Jeng Yeong, Go, Maybelle Kho, Yew, Wen Shan
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780937/
https://ncbi.nlm.nih.gov/pubmed/26779961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53243
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