Directed Evolution of a Thermostable Quorum-quenching Lactonase from the Amidohydrolase Superfamily

A thermostable quorum-quenching lactonase from Geobacillus kaustophilus HTA426 (GI: 56420041) was used as an initial template for in vitro directed evolution experiments. This enzyme belongs to the phosphotriesterase-like lactonase (PLL) group of enzymes within the amidohydrolase superfamily that hy...

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Hlavní autoři: Chow, Jeng Yeong, Xue, Bo, Lee, Kang Hao, Tung, Alvin, Wu, Long, Robinson, Robert C., Yew, Wen Shan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003391/
https://ncbi.nlm.nih.gov/pubmed/20980257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177139
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