AAVP displaying octreotide for ligand-directed therapeutic transgene delivery in neuroendocrine tumors of the pancreas

Patients with inoperable or unresectable pancreatic neuroendocrine tumors (NETs) have limited treatment options. These rare human tumors often express somatostatin receptors (SSTRs) and thus are clinically responsive to certain relatively stable somatostatin analogs, such as octreotide. Unfortunatel...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Smith, Tracey L., Yuan, Ziqiang, Cardó-Vila, Marina, Sanchez Claros, Carmen, Adem, Asha, Cui, Min-Hui, Branch, Craig A., Gelovani, Juri G., Libutti, Steven K., Sidman, Richard L., Pasqualini, Renata, Arap, Wadih
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780640/
https://ncbi.nlm.nih.gov/pubmed/26884209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1525709113
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